Project

Analysis of Gene Co-expression Networks of Two Coccolithophore Species

Gene Co-Expression network involves nodes which corresponds to genes and edges corresponding to co-expression relationship between genes. Such networks enable the inference of diseases and system-level functionality of genes. These inferences are helpful in identifying genes characteristics. In this project, E. Huxleyi and G. Oceanica RNA-Seq data was compared with each other and divided into different co-expressed group of genes between two species also called as ‘modules’. These modules are then compared with external traits to find out how the modules and traits are related. Functional enrichment analysis was performed on these modules to identify significantly enriched genes in the interesting modules. After the analysis, by using highly preserved modules in both the data sets, lipid metabolism genes and biomineralization genes to these modules are related and biological functions for these genes are obtained. Similarly, lists of genes which can be related to set of biomineralization genes was obtained which can vastly help us study biomineralization process in detail in the two species.

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